A consensus framework for digital twin development in lyophilization

Published in AAPS Open, 2026

Large collaborative paper describing the state of the art and frameworks for adopting digital twins in lyophilization (that is, making feedback control possible).

Recommended citation: Kazarin, P., Metsi-Guckel, E., Alexeenko, A., Tchessalov, S., Aglave, R., Al Bakri, W., Authelin, J.-R., Dowling, D., Ganguly, A., Gong, E., Horner, M., Fontana, L., Iyer, L., Kessler, W., Kiehl, D., Lapointe-Garant, P.-P., Longwell, G., Moussa, E., Najarian, J., Saha, K., Sebastiao, I., Shalaev, E., Tukra, R., Vorozhbit, E., Wheeler, I.S., Bhatt, S. (2026). A consensus framework for digital twin development in lyophilization. AAPS Open, 12(1), 52. https://doi.org/10.1186/s41120-026-00150-w
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