Direct Modeling of Pore Size Evolution and Microcollapse in Lyophilization by Population Balance
Posted to arXiv, 2026-10-02.
Work that resulted from my my time spent as a Fulbright grantee, doing an exchange at the Politecnico di Torino in Italy.
We developed a model for the evolution of pore size distributions during lyophilization, which accounts for process conditions to predict how microcollapse changes the mass transfer resistance over time.
Citation: Isaac S. Wheeler, Vivek Narsimhan, Alina Alexeenko, Davide Fissore. Direct modeling of pore size evolution and microcollapse in lyophilization by population balance. arXiv preprint arXiv:2610.01851 (2026). doi:10.48550/arXiv.2610.01851
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